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Its Canonicity is in question but was once considered canon.
The Destructor is a Dark Eldar weapon used primarily by Haemonculi. It resembles a long tube, with a cavity to slip one's hand into up to the elbow. The ammunition for the weapon is carried in a small container the Haemonculus wears, fed through a series of tubes. The Destructor sprays a wide stream of an incredibly corrosive organo-acidic compound when fired. This toxin can eat through any known armour, burn flesh, and once inside the target's system can cause, "blood vessel explosion or implosion; pharyngeal contraction; extensive haemolysis; skeletal disintegration; sclerotic corrosion; intercostal spasms; hyper-reacted thermoreceptors and chemoreceptors; Eustachian damage; retinal scarring; cardiac and respiratory atrophy and aqueous humor deprivation."[Needs Citation]
This device's effectiveness in combat has been confirmed time and again, with reports of a single Haemonculus able to decimate an entire squad of Space Marines with a single well-aimed volley, every man among them dying from sheer pain, or worse, leaving them alive but immobilized - blind, hideously burned, hemorrhaging blood from every orifice, wracked in unimaginable amounts of agony, helpless and in the twisted hands of the Haemonculi.