From Lexicanum

Gholams are an artificial construct that are made primarily by flesh and synthetic tissue that can be created by the Adeptus Mechanicus of the Imperium. The art of making these constructs is through that of a gene-sculptor and are a widespread piece of technology within the Adeptus Mechanicus. However, many branches of the lore to create a Gholam are considered both heretical and forbidden. The reason for this is because of the more violent applications of the technology such as the horrific organic fabrications known as Murder Gholams which are intended for nothing more than violence.

The heretek cult known as the Logicians have been known to pursue examples of Gholams.¹

Source

• ¹:Dark Heresy Disciples of the Dark Gods by Fantasy Flight Games (pg 44)

External Link

• Fantasy Flight Games