From Lexicanum

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House Escher is a group of gangs in the Hive Primus of the Hive World Necromunda. The house is controlled by its female members since the male Eschers are considered inferior specimens due to a genetic deviation. As such, all of the members of House Escher are female, but this should not lead to underestimating them since they are fast, agile and deadly fighters. Female refugees from the spire of the Hive such as "Mad" Donna Ulanti and Yolanda Catallus who become bounty hunters and occasionally partners to Kal Jerico are often associated with House Escher.

The borders of House Escher meet the ganglands of House Goliath who are seen as as brainless by the members of Escher, due to their frequent display of their muscles. They are often called "Meatnecks". When a group of women lost a fight against Goliath, they formed a community deep in the underhive of Necromunda.

Their relations with House Orlock is traditionally good as they treat their wives well and relationships continue to improve as the present leader of House Orlock is married to a woman from the Ulanti family from the spire.

Sources

• Necromunda Rulebook - rule and background book
• Necromunda Underhive - expansion book
• Kal Jerico (Comics)