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First conquered during the Great Crusade by Rogal Dorn, by the time of the Horus Heresy the planet was conquered by the Sons of Horus, who gave it over to the machinations of Fabius Bile. Bile conducted grotesque experiments on the inmates there, many loyal Imperial citizens among them.
The Raven Guard led by Corax himself eventually made a move to liberate Carandiru, waiting for Commander Soukhounou to instigate an uprising among the civilians and inmates of the planet. As chaos gripped the penal world, Mor Deythan squads landed and seized key power generators, disabling anti-air defenses and cutting enemy communications. Raptors led the main attack, sweeping aside resistance until encountering the Enhanced Warriors of Bile. Corax himself was nearly overcome by these fearsome creatures until Commander Gherith Arendi saved him. In the end, the Raven Guard was victorious in driving off the Traitors.