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A staunch [[Amalathian]], Karamazov is bitterly opposed to the notion of change, believing that the [[Emperor]]'s plan for His people must be left to unfold as He planned and without the arrogant intervention of those who believe that they understand His will. He is a harsh judge and brooks no pleas of innocence, once famously boasting that he has sent more [[witches]] and [[heretics]] to their deaths than [[Macharius (Character)|Macharius]].{{Fn|1}}
Karamazov has risen steadily in the [[Ordo Hereticus]] for decades, acquiring many supporters within the more hard-line [[Puritan]] elements of the Inquisition for his unflinching determination to punish witchcraft and heresy without mercy. His deeds were repute with the rigid application of the [[Imperial Creed]] and, though some within the Inquisition criticised his inflexibility and claimed that he had sent thousands of innocents to their deaths, Karamazov would reply with Judge [[Traggat]]'s famous maxim that ''"claims of innocence meant nothing; serving only to prove a foolish lack of caution."'' His purges have become infamous, particularly those carried out on [[Ultima Macharia]], [[Bakka]], and [[Cypra Mundi]]. After the [[Abraxan Purges]] of 930.[[M41]] he was presented with his mighty [[Throne of Judgement]], which was buried within the '''Crypts of Abraxras''' and which and which has since become a symbol of his Karamazov's power and prestige.{{Fn|2}}
Karamazov's reputation as a ruthless, unforgiving [[Witch Hunter]] was already well known throughout [[Segmentum Solar]] when he famously clashed with [[Ecclesiarch]] [[Decius XXIII]] concerning Karamazov's [[excruciation]] and eventual immolation of a young preacher from the world of [[Salem Proctor]] in 945.[[M41]]. This world had broken faith with the [[Ecclesiarchy]], its apostate [[cardinal]] turning the world's resources to his own ends and casting out all who defied him. Inquisitor Lord Karamazov led a fleet, together with two entire orders of the [[Adepta Sororitas]], to depose the apostate cardinal, but upon its arrival, he found the world already in rebellion against its traitorous ruler.{{Fn|1}}
